The Chambers County Museum is a museum in LaFayette, Alabama. It features mainly the local history of the area, with displays that tell of the development of the region through artifacts and other items on exhibit.

Housed in the historic Central of Georgia railway depot built in 1908, the Chambers County Museum shares a number of interesting items under its roof. Some of which comes with the building, like the large scale that is built into the floor and the names of the old local businesses that are still engraved on the walls of the freight room. There is also a collection of regional stoneware made in the early days of the state, as well as a section dedicated to Joe Louis, a former world heavyweight boxing champion who was born nearby.

The Chambers County Museum is open every Wednesdays and Saturdays.