The Russian American Building No. 29 is a historic site in Sitka, Alaska. It is a basic siding covered log building that was built in 1850, years before the state of Alaska was purchased by the United States.

Also known as the Tilson Building, the Russian American Building No. 29 is historically and architecturally significant for being a rare illustration of a Russian-American colony building. As it was built before the state of Alaska became a part of the United States, it is also noted for being a witness of the Russian colonization of what is now a US territory.

The Russian American Building No. 29 was declared a National Historic Landmark in May 1987, the same day that it was listed on the National Register of Historic Places.