The Cossatot River State Park-Natural Area is a state park and a natural area in Wickes, Arkansas. It features 5383 acres of area.

Established in 1988, the Cossatot River State Park-Natural Area features the Cossatot River, which is a part of the Natural and Scenic Rivers System under the National Park Service. The upper area of the river is a National Wild and Scenic River and is largely undeveloped and left to its natural state. Aside from the spectacular scenery, the park also offers the public the opportunity to see over thirty rare plant and animal species, among other kinds of plant and wild life.

Visitors of the Cossatot River State Park-Natural Area can also enjoy camping, hiking, kayaking, and nature study at the site.