The Hampson Museum State Park is a state park and museum in Wilson, Arkansas. It is best known for being the home of a nationally renowned collection of artifacts recovered from the Nodena site.

The Nodena Site is a National Historic Landmark that dates back to 1400 to 1650 CE. It is a 15-acre palisaded village on the Mississippi River, now known as the Mississippi County. The early inhabitants of the area were farmers who also hunted native game. The artifacts recovered from the site are interpreted and displayed at the Hampson Museum State Park.

Named after the local landowner and archaeologist, Dr. James K. Hampson, the Hampson Museum State Park offers guided tours on any day that the museum is open.