Successful oil magnate Edward Laurence Doheny gave his son, Edward Laurence Doheny, Jr., and daughter-in-lawl, Lucy, the 12.58 acres of land he acquired in 1914. On this land, the Greystone Mansion was constructed.

With a cost of $3,135.563, the mansion was the largest undertaking of a family estate in Beverly Hills at that time.

In 1926, the construction for the mansion began. Using the design of Paul Thiene, it combined the beauty of English and Italian gardens. The plants and flowers found in the garden are composed of almost 100 different species coming from all over the world. As for the structure, architect Godron Kaufman designed the mansion as a 19th century English revival house with its interiors boasting of 18th century styling.

Today, the Greystone Mansion provides a venue for cultural and educational activities as well as movies, television shows, commercials, and photo shoots.