The Butler House Museum is a historic house museum in Deerfield Beach, Florida. It is also known as the James D. and Alice Butler House.

The Butler House Museum was created by the Deerfield Beach Historical Society as a means to preserve it. It was acquired by the organization in 1977 and was restored immediately and served as the home of the group ever since. They also opened the site as a museum, featuring the original furnishings of the house, depicting the life and times of the Butler family in the residence.

Built in 1923, the Butler House Museum is just one of the four local sites that the society helped salvage and get listed on the National Register of Historic Places.