The Government House Museum is a history museum in St. Augustine, Florida. It features the historic Government House, which dates back to the earliest days of the colonial period.

The Government House Museum commemorates the long history of the city, as manifested by the building, which goes as far back to the mid 1500s, along with the old Plaza of the city. Although, technically, the structure was only built in 1710, rebuilt after the British destruction of the city, it is still one of the oldest structures around. It has served several purposes in the past, mostly having something to do with public governance.

The Government House Museum was created in 1991 and showcases numerous different historic displays and exhibits.