The Raney House Museum is a historic house museum in Apalachicola, Florida. It is housed in a National Register of Historic Places listed site, the David G. Raney House.

The Raney House Museum features the Raney House. Built in 1838, the structure is considered to embody the Southern flair. It also tells the tale of the city of Apalachicola, being built during the time when the locale was still growing and is the third busiest port on the Gulf of Mexico. It is packed with 19th century furnishings, artifacts, documents, and decorations.

The Raney House Museum is open on Tuesdays through Thursdays from 1 to 4 pm and on Saturdays from 9 am to 5 pm. Admission to the museum is free.