If you're looking for a good local brewery with great beer, atmosphere and food, check this place out: Brugge Brasserie. It's in Broad Ripple. I'm not a local but was there a few times in the past year for business. This was my favorite spot to go.
The beer there is awesome, the food is even better. The only downside is the service is spotty. Sometimes it's really good as I understand it, but the last time I was there we were practically ignored by our server all night. It was a pretty terrible experience.
The beer is amazing. But also pretty strong, watch out. Enjoy the food and drink, but be prepared for so-so service. Interesting Fact-- Its part owned by the big guy from the TV show Parker Lewis Can't Lose.