The Juliette Gordon Low Birthplace allows visitors to learn more about the founder of the Girl Scouts of the United States, who was born with severe hearing loss. The place is the first National Historic Landmark of the city and also served as home to James Moore Wayne, a SC Justice, and W.W. Gordon, a general during the Spanish-American War.

The property was purchased by Wayne, who was also a mayor of Savannah in the 19th century, in 1818. The style of architecture for the double house was typical for local residents in those days and was known collectively as ?Savannah boxes?. The historic home, however, was made distinct by its larger proportion and the impressive architectural details found in its interior and exterior.