Built by Great H. Hollenberg in 1858, the Hollenberg Pony Express Station, also called the Cottonwood Pony Express Station, is a historic site, related to the legendary Pony Express, Oregon and California Trails, and the Butterfield Overland Mail. Its builder and owner used the structure to trade with the emigrants passing through the trails, provide overnight lodging, supplies, and meals to travelers, did relay services of the Overland Mail, and operated the westernmost Pony Express station in the state.

The Hollenberg Pony Express Station is now called the Hollenberg Pony Express Station State Historic Site, located in the Hollenberg Ranch State Park. It is operated by Kansas Historical Society and has been declared as a National Historic Landmark in 1966.