The Isaac Shelby Cemetery State Historic Site is a historic site and state park in Stanford, Kentucky. It marks and preserves the site where the estate once stood and grave of Isaac Shelby is found.

Isaac Shelby is a soldier, statesman, and surveyor. However, his most noted achievement is for being the first governor of Kentucky. He served in office from 1792 to 1796 and got re elected in 1812. He was also highly esteemed for his accomplishments in education, politics, and military that in his honor, several counties in nine states were named after him. The Isaac Shelby Cemetery State Historic Site is the site of his old estate and where his family cemetery is located.

The Isaac Shelby Cemetery State Historic Site became a park under the Kentucky state parks system in 1951.