The Karpeles Manuscript Library Museum is seen in a Christian Scientist Church building that was built last 1912. It is housed in a beautiful structure that comes with a huge main floor to serve as its exhibit halls. With its ceilings very high, you can find the acoustics of the place excellent. It is then made perfect to hold musical concerts along with other artistic programs.

The museum also offer outreach programs which provide historical artifacts on very special displays which help students and researchers be educated all the more. It also renders special lectures to various schools in the Duluth area to discuss and explore topics which are all related to documents and antique manuscripts used for display in museums.