The Greenwood Blues Heritage Museum & Gallery is a music museum in Greenwood, Mississippi. It is focused on information about the Delta blues.

Opened in November 15, 2001, the Greenwood Blues Heritage Museum & Gallery is mostly a tribute to one of the best Delta blues musician, Robert Johnson. Johnson is a widely known musician from the mid-1930s who showed much promise but died at the early age of 27. Due to his shadowy and poorly documented life events, legend has it that he sold his soul to the devil to gain unrivaled musical prowess.

The Greenwood Blues Heritage Museum & Gallery features the largest collection of materials that are related to Johnson. It includes his music, photographs, and awards among other things. There are displays about other local Delta blues musicians as well.