The Casa Mesita Thrift Shop is a local business in Los Alamos, New Mexico. It is noted for its philanthropic activities and its great selection of odd things for sale.

Although, most thrift shops are slowly gaining fame in the recent years all thanks to the trends that are in vogue nowadays, the Casa Mesita Thrift Shop has always been quite a tourist attraction in its own right. It is a second hand store where locals tend to take their “odds and ends” to. But what makes it really special is that it is also a supporting venture to the Casa Mesita Group Home. This organization serves as a group home for girls who are from “difficult domestic environments”.

The Casa Mesita Thrift Shop is volunteer run entirely.