The Las Cruces Railroad Museum is a railroading museum in Las Cruces, New Mexico. It is focused on the railroad history of the city and its impact on the Southern New Mexico region.

Like most cities and towns in the United States, being connected to a railroad system helped Las Cruces to be what it is today. Being connected to the rest of the New World aided its growth from a sleepy town to a bustling city filled with businesses and opportunities. These things are the main topics of the Las Cruces Railroad Museum.

Housed in the historic Santa Fe Railroad depot, the Las Cruces Railroad Museum is packed with information and displays telling of the rich history of the area. It is open on Thursdays through Saturdays from 9 am to 4:30 pm.