The New Mexico State University Art Gallery is an art museum and gallery in Las Cruces, New Mexico. It is best known for its unique permanent collection and displays.

Featuring more than 3000 art works from its permanent collection and traveling exhibits, the New Mexico State University Art Gallery is mostly an exhibit space for works of university faculty and students. However, it is also noted for its historical collection which is mostly composed of Mexican retablos or devotional paintings on tin that is considered as the largest collection in the United States. The site also hosts educational programs, outreach activities, and other events.

The New Mexico State University Art Gallery is open regularly from Tuesdays through Saturdays at varying schedules depending on the season.