The Arboretum and Garden at Tanglewood is a garden and arboretum located in Clemmons, North Carolina, inside the Tanglewood Park. It is a remembrance of the Tanglewood Arboretum that Sir Walter Raleigh claimed for Queen Elizabeth in 1584.

The Arboretum and Garden at Tanglewood traces its history back to 1921, when the park was created by Mr. and Mrs. William Neal Reynolds. The park was then passed on to the citizens of Forsyth County when the Reynolds passed away in 1951. They redesigned the site, which also paved the way for the beginnings of the arboretum.

Today, the Arboretum and Garden at Tanglewood is a great place to see various plant varieties that are from the different parts of the world.