The John Wesley McElroy House is a historic home in Burnsville, North Carolina. It is a Federal Greek revival style structure that was built in the 1840s and was listed on the National Register of Historic Places in November 1990.

The John Wesley McElroy House was built and named after John Wesley McElroy, a local lawyer and businessman, who also served as a brigadier general for the Confederate Army. He had the mansion built for his wife Catherine. The house was also used as a hospital and headquarters during the Civil War and became the residence of former state senator and Union Army captain, William Moore. The house was also the first Post Office in town.

Today, the John Wesley McElroy is known and operated as the Rush Wray Museum of Yancey County History.