In the Hutchinson?s Warehouse in Rantowles, South Carolina, the very first slave revolt took place in 1739. It was named the Stono Rebellion, also known as the Cato?s Conspiracy or Cato?s Rebellion, after the individual who started it all. Known as ?Cato? or Jemmy (probably owned after the Cato or Cater family), he recruited up to 60 slaves to his cause. They killed up to around 25 white men before they got intercepted by the South Carolina militia. The Stono Rebellion was the largest uprising of its sort in a British colony before the American Revolution.

The location where the rebellion took place is preserved and maintained as the Stono River Slave Rebellion Site. It is a declared National Historic Landmark.