The Huntsville Historic Depot is a museum located in Huntsville, Alabama. It is a part of the Earlyworks Museum Complex. It features the 1820 railroad depot that helped Huntsville achieve the title of being a frontier community.

The Huntsville Historic Depot chronicles the impact of the railroad that was built nearby. Anyone who is familiar with history knows that any town that has a train station back in the early days is already slated for great things. Their economies were affected largely by the ease of transportation, making it a really great place to be in.

The Huntsville Historic Depot is historic in its own right, being around for almost two centuries now. It was restored in it 1860s state and features a number of items that tells visitors of the railway history of Alabama.