The David and Rachel Caldwell Historical Center is a historic site in Greensboro, North Carolina. It is dedicated in telling and sharing the history of the Caldwell couple, who has made such a great impact in the area, even before the city of Greensboro was created in 1808.

The Caldwells found their way into the Greensboro area in 1765, when David was assigned to become the minister of the Buffalo Presbyterian Church and then of the Alamance Presbyterian Church. They have set up a farm on the site, where they also set up their academy and began molding young minds from the area.

The David and Rachel Caldwell Historical Center features the life and times of the Caldwell couple through artifacts and historic items found in the area.