The Lenoir Store is a historic general store in Horatio, South Carolina. It is named after the family that has owned and operated it since before 1808 when the earliest records of were traced to. It is dubbed as the oldest business establishment in the county of Sumter.

The exact date of when the Lenoir Store was built is unclear. It is theorized that the current structure can be a replacement of an older one, as some records say that the business was already in operation during the early 1800s. Some say that the current structure is built before 1878, but no definite dates are pointed out.

An excellent example of the ?old general store?, the Lenoir Store was listed on the National Register of Historic Places in 1997.