Formerly known as the Trinity Episcopal Church, the Trinity Episcopal Cathedral is a historic religious site in Columbia, South Carolina. It is the first Episcopal sanctuary in the city, which also makes it the oldest surviving structure of the sort in Columbia as well.

Built in 1847, the Trinity Episcopal Cathedral housed the Society for the Advancement of Christianity in South Carolina. The current structure is actually a replacement of the 1814 wooden one, which was initially built when the congregation formed.

Saved from the burning during the Civil War when General WT Sherman replaced the Episcopal signs with paper mache crosses, the Trinity Episcopal Church was spared from the tragic fate of other Episcopal churches in the country. This allowed it to survive until today.