Originally Posted by IslandTJ
Per capita, don't we have the most?
We lost that title to Asheville, NC sometime in the last couple of years. And since their population is so small, we'd need something like 20 more breweries to reclaim it. However, at this point I think we could make a run for most breweries, period.
Best numbers I can dig up right now are 10 breweries to 125,000 people in Asheville and 28 breweries to 582,130 people in Portland. Unfortunately, all these numbers are moving targets.
from Breweries in Portland, Oregon - Travel - New York Times
Portland has more breweries - 28 - than any other city in the nation if not the world, and it has arguably become one of the best destinations anywhere for beer-tasting.
However, to get to the OP's question, I think the chain breweries have been laying out map of the city with breweries to make sure that there are few under-served neighborhoods. Certainly none come to my mind; the McMenamin's, New Old Lompocs and Lucky Labs are everywhere.